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Aquashine BR

Aquashine BR

AQUASHINE is an anti-wrinkle and skin rejuvenating mesotherapy product composed of bioactive ingredients including hyaluronic acid, multi-vitamin and amino acids.

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Description

AQUASHINEBR is a skin rejuvenating and anti-pigmentation mesotherapy product composed of bioactive ingredients including hyaluronic acid, multi-vitamin and amino acids.

Benefits of active ingredients:

-Reduce wrinkles and improve skin elasticity by generating new skin cells.
-Revitalize tired and dull skin by maximizing cell proliferation and reducing skin problem.
-Reduce and prevent hyper-pigmentation, down-regulates melanin synthesis, thereby reducing  skin pigmentation, aged spots and freckles.
-Pure Hyaluronic acid moisturizes skin and tightens pores

Key ingredients of REVOFIL Aquashine and REVOFIL Aquashine BR

1. Rejuline (Acetyl Decapeptide-3)
The microscope image (X400) of skin section of histochemical staining (H&E staining) after 14days treatment of Rejuline (10ppm) containing cream.

2. CG-TGP2 (Oligopeptide-34)
In cell morphology comparison, we observed the decreased melanosome formation in CG-TGP2 treated melanocyte cell line.

3. CG-EDP3 (Oligopeptide-24)
Regulation of Hyaluronic Acid and Elastin Expression

4. CG-Purilux (Oligopeptide-51)
Morphological Change of Melanocyte Cell Line

Properties

Concentration of HA: 15mg/mL

Needle: 32G 1/2

Indication: Hydration, Radiance/Skin Brightening, Elasticity, Wrinkles and Fine Lines

Skin Rejuvenating Complex: 4 peptides, 24 amino acids, 14 vitamins, 8 minerals and coenzyme

Injection depth: Epidermal / Superficial to Mid Dermis

Injection area: Face / Neck / Décolleté

Blister pack: 2mL Prefilled syringe / Pack

Injection Area: 3 sessions at 4-week intervals

Before & Аfter Pictures

Sex: Female
Age:
Late 50’s
Product: REVOFIL Aquashine BR
Injection Area: Cheek and Nasolabial area

FAQ

If you want to look yourself more beautiful and younger, but want to avoid the pressure of surgery, REVOFIL could be right for you. This is a safe material with natural compounds in our body but sythesized outside the body.
Our research indicates that a large number of people would like to return their beauty in a natural, non-permanent way. They are also concerned about potential scarring or other aftereffects. REVOFIL answers these concerns Injecting REVOFIL is an uncomplicated with minimal time away from work and daily activities as a result.

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The safety of REVOFIL has been thoroughly evaluated based on the standards of medical devices and then clinically proven. In our in-vivo test, one hundred seventy-two patients were injected with REVOFIL Ultra(56), REVOFIL Plus(86),REVOFIL Fine(30) and REVOFIL AQUASHINE and AQUASHINEBR were also clinically tested on the suitable standards for those who are aged 20 ~56.
All patients were satisfied after injection with no allergic reactions.
There’s no side effect of REVOFIL reported, the only issue could be from injection technic or the condition of treatment, you might experience some redness or a bit of swelling as being injected but it would be disappeared in a day.  Those reaction could depend on sensitivity of each skin.

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1) Non comparably long duration: At least 10 ~ 12 months.

2) Extraordinary effects on collagen synthesis and skin firming by biomimetic peptides in Dermal Filler.

3) Safe and high quality product

Category: Revofil

We divided the REVOFIL into 3 types by viscosity for applications. (The cross linkage is based on the reaction time with cross linking agent hence the viscosity is different.)
The size of needles:
REVOFIL Ultra – 27G
REVOFIL Plus – 27G
REVOFIL Fine – 30G
REVOFIL Aquashine – 32G
REVOFIL Aquashine BR – 32G

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There is no problem, it would be good for tissue relax.

Category: Revofil

Almost right after the injection. Ice pack cooling massage could help to reduce the redness and swelling.

Category: Revofil

The procedure takes around 30-90 minutes depending on the area treated and the quantity of gel injected. The result can be seen immediately.

Category: Revofil

We have the affirmative results reached by 99% in the clinical study. The effectiveness of treatment shows visible volumizing effect on lips, nose, hands and other parts, the patients wanted to be improved. Also, various kinds of facial wrinkles were decreased or disappeared especially around the eyes.

Category: Revofil

In-vitro test data compared REVOFIL to competitors in market, showed that Collagen and Hyaluronic Acid were less affected by enzymatic degradation.
REVOFIL breaks down slowly and the efficacy lasts longer.

Category: Revofil

REVOFIL brings aesthetic improvements on your face and body with fast and less painful procedure. The hyaluronic acid and biomimetic peptides maintain long-lasting volumizing and lifting efficacy.

Category: Revofil

The HA gel combined with biomimetic peptides enables facial implant to last longer than competitors and promotes collagen synthesis and anti-wrinkle & skin firming effects.

Category: Revofil

Biomimetic peptides provide additional ionic bonds to cross linked (or non-cross linked) HA leading to improvement of rheological properties of REVOFIL with better elasticity and stability. Hyaluronidase resistance is also enhanced by ionic bonds.

Category: Revofil

REVOFIL is basically biphasic gel which has stronger resistance to Hyaluronidase activity than monophasic. However, biomimetic peptides in REVOFIL are linked by ionic bondage with HA gel which makes texture as soft as monophasic.

Category: Revofil

Both of REVOFIL and REVOFIL AQUASHINE contains highly purified HA and basically they are different from whether HA was cross-linked or not.
Accordingly REVOFIL is more specialized augmentation and volumizing along with skin rejuvenation while REVOFIL AQUASHINE is mainly working for skin rejuvenation through hydration and brightening with cocktail of peptide complex, amino acids, multi-vitamin, minerals, etc.

Category: Revofil

AQUASHINE was designed for hydrating and rejuvenating efficacy with anti-aging cocktail. And AQUASHINEBR was focused on anti-pigmentation and skin brightening cocktail.

Category: Revofil

AQUASHINE:
-Reduce wrinkles and improve skin elasticity by generating new skin cells.
-Revitalize tired and dull skin by maximizing cell proliferation and reducing skin problem.
-Pure Hyaluronic acid moisturizes skin and tightens pores

AQUASHINEBR
-Reduce wrinkles and improve skin elasticity by generating new skin cells.
-Revitalize tired and dull skin by maximizing cell proliferation and reducing skin problem.
-Reduce and prevent hyper-pigmentation, down-regulates melanin synthesis, thereby reducing skin pigmentation, aged spots and freckles.
-Pure Hyaluronic acid moisturizes skin and tightens pores.

Category: Revofil

During our research we found that 1 ml is not enough for the treatment. Many doctors prefer to work with 2ml volume.

Category: Revofil

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Revofil

About Revofil

CAREGEN Research Center offers you perfect solution for face and tissue remodeling.
REVOFIL is a new generation filler that can last longer than other existing HA dermal fillers.

REVOFIL KEEPS AND MAINTAINS YOUR BEAUTY TODAY AND TOMORROW!

REVOFIL is made from high quality ingredients using innovative technology of CAREGEN Research Center – the leader of Bio actives and cosmeceuticals in the world. Advanced peptides development constantly provides you safe and perfect result saving your time, energy and money.

Product

We have succeeded in developing Innovative Dermal HA Filler. REVOFIL giving you a long lasting result generates endogenous HA, elastin, collagen, and other ECMs (Extracellular Matrix) refresh natural colors of your beauty.

REVOFIL present you long lasting desirable lines and features to Stay Longer, Stay Active and Stay Spectacular.

Philosophy

Cosmetic products should make you more beautiful and support your beauty as long as it possible and beyond. We are making sure to present such service to our customers.

Technology

CAREGEN has been developed its biotechnology innovative discoveries for more than 10 years to our valuable customers.
We know very well the miracle results of our biomimetic peptides.
Experience our new discoveries and share this experience with others.

Safety

The results and opinions from the clinical study done for CE certification under its strict regulation for REVOFIL Fine, Plus, Ultra, Aquashine and Aquashine BR are summarized as below:

1) In most clinical cases, tissue improvement was observed in various part of skin.
2) No major side effects requiring medical attention were observed.

From the clinical
observation made in this test with REVOFIL Fine, Plus, Ultra, Aquashine and Aquashine BR and broad experience of investigator in use of similar commercially available therapy, it can be said that REVOFIL Fine, Plus, Ultra, Aquashine and Aquashine BR possesses all physical, structural and biocompatibility properties that are required of a superior gel for used in skin restoring.

Name of Tests Conducted

1.Sterility Test 
This test was conducted to test suitability and validation for bacteriostasis and fungistasis.in accordance with “The Korean Pharmacopoeia
(9th Edition:2007)”

2. Endotoxin Test 
(LAL test)This test was conducted to detect and quantify endotoxins in REVOFIL in accordance with “The United Stated Pharmacopeia (USP 31)”.
<85>Bacterial Endotoxins test and “The Korean Pharmacopoeia
(9th Edition:2007)”

3. Skin sensitization Test
This test was conducted to evaluate the skin sensitizing potency of REVOFIL injection.

4. Acute Toxicity Test
This test was performed to investigate the acute toxicity when
REVOFIL injection.

5. Intracutaneous (intradermal) Reactivity Test
This test was performed to investigate irritation potency
(erythema and edema) for intradermal injection of REVOFIL.

6. Cytotoxicity Test
This test was conducted to evaluate the potential for cytotoxicity in-vitro in accordance with International Organization for Standardization 10993: Biological Evaluation of MedicalDevices, Part 5: Tests for
Cytotoxicity: in vitro Methods (ISO 10993-5).

7. Intracutaneous (intradermal) Reactivity Test
This test was performed to investigate irritation potency
(erythema and edema) for intradermal injection of REVOFIL.

8. 12-week Subcutaneous implantation test of REVOFIL (Injection)
This test was conducted to investigate the local response
(clinical sign, mortality and etc) of
subcutaneous tissue in REVOFIL injection.