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Prostrolane Natural B

Prostrolane Natural B

Over time, there are number of factors that affect the way skin looks. Sagging skin occurs as we age and our skin loses elasticity.

Prostrolane Natural B injectable gel is indicated for deep dermis implantation for the correction of moderate to severe facial wrinkles, folds and perioral lines. Prostrolane Natural B aims for giving natural look and feel.

New Innovative Injectables with Sustained Release Technology & Novel Peptide Technology for Body Slimming, Anti-Aging&Anti-Pigmentation.

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Description

Active Ingredients
Oligopeptide-24, Decapeptide-36, Octapeptide-11, Oligopeptide-34, Oligopeptide-92

Capacity
2ml gel in prefilled syringec

Recommended dosage and sessions :
1 session every 2 weeks

Total session :
2 sessions

Advantages
– Natural Look
– Skin Rejuvenation
– Correction of facial wrinkles

Regulation of Aquaporin3 Gene Expression
Cell: HaCaT Keratinocyte / Culture time: 12, 24hours
Method: RT-PCR analysis

Regulation of Collagen expression Cell:
NIH3T3 Fibroblast / Culture time: 48hours
Method: Immunocytochemistry assay

Indications

Prostrolane Natural B injectable gel is indicated for deep dermis implantation for the correction of moderate to severe facial wrinkles, folds, and periorals lines. Prostrolane Natural B aims for giving natural look and feel.

Properties

Prostrolane Natural B injectable gel is indicated for deep dermis implantation for the correction of moderate to severe facial wrinkles, folds, and periorals lines. Prostrolane Natural B aims for giving natural look and feel.

 

Injection Interval:
1 session every 2 weeks (Total 2 sessions), If necessary, retouch after 2 months.

Injection Depth:
Intradermal layer of targeted area

Injection Volume:
Inject 0.05ml~0.2ml(cc) per targeted point

 

Treatment Method

Increased expression of ECM molecules such as collagen, ellastin and fibronectin.
Inhibition of MMP 2/9 activity(MMP 2/9 is mainly down-regulate of collagen generation and synethsis)
Increased expression of Aquaporin3 and SIRT1 which are highly related with skin hydration.
Inhibition of pro-inflammatory cytokine such as TNF- α, IL-6 and COX 2.
Keratinocyte Activation.
Inhibition of expression of reactive oxygen species
which induce deformation of normal cell.

In-vitro Test Data

Before & Аfter Pictures

Nasolabial / Under Eyes (2 syringes per session(3 sessions)

Nasolabial / Fine wrinkles (2 syringes per session(3 sessions)

Nasolabial / Fine wrinkles (4 syringes per session (3 sessions))

Nasolabial / Fine wrinkles (Natural B 1 syringe per session (1 session)

Platform Technology

Growth Factors
SUPERIORITY OF GROWTH FACTORS
– Competitive price based on mass production technology
– High efficacy and stability by double-layered capsulation technology
– High punity by sophisticated production facility and technical superiority

Biomimetic Peptides
ADVANTAGES OF BIOMIMETIC PEPTIDES
– Sustainable new biomimetic peptides development
– Competitive price based on mass production technology
– High punity by sophisticated production skill based on technical superiority

Skin Delivery System
DOUBLE-LAYERED CAPSULATION TECHNOLOGY
– High stability by double-layered structure
– High homogeneity : average diameter of particle is 140nm and over 80%
particles are below 100nm in size
– Effcient delivery of therapeutic cosmetic components into dermal layer

Skin Stem Cell Research
Skin Stem cell is a type of blast cell, Which can differentiate to various adult cells
including skin cell and hair cell. Caregen has focused on skin stem cell
differentiation to skin keratinocytes for Anti-aging.

Patents

– 21Growth Factors Registered in PCPC.

– 188 Biomimetic Peptides registered in PCPC.

– Multiple patents 123 patented materials in Korea, USA, Japan, China and Europe etc.

Certification & Accreditation

– Multiple patents over 100 patented materials in Korea, USA, Japan, China and Europe etc.

– CE Certificate, ISO 9001, 14001